Adaptogens: Ancient Herbs, Modern Stress

Adaptogens: Ancient Herbs, Modern Stress

8 min read

Ashwagandha, rhodiola, holy basil — adaptogenic herbs have been used for centuries to help the body handle stress. Here's what the research actually says.

Adaptogens are a class of herbs and mushrooms that help the body adapt to stress — physical, chemical, and biological. The term was coined by Soviet pharmacologist Nikolai Lazarev in 1947, and the concept has been validated by decades of subsequent research. What makes an adaptogen distinct is its ability to normalize physiological function regardless of the direction of the stressor.

Ashwagandha (Withania somnifera) is the most studied adaptogen for stress and cortisol reduction. Multiple randomized controlled trials show that 300 to 600mg of ashwagandha root extract daily significantly reduces cortisol levels, perceived stress, and anxiety. It also improves sleep quality and thyroid function in women with subclinical hypothyroidism.

Rhodiola rosea has the strongest evidence for fatigue and cognitive performance under stress. It works differently from ashwagandha — rather than primarily reducing cortisol, it appears to support the body's stress response system more broadly, improving mental clarity and physical endurance during demanding periods.

Holy basil (Ocimum tenuiflorum), also called tulsi, is an Ayurvedic adaptogen with anti-inflammatory and blood sugar-stabilizing properties in addition to its stress-modulating effects. It is most commonly consumed as a tea and has a pleasant, slightly clove-like flavor.

A few important caveats: adaptogens are not regulated as drugs, quality varies enormously between products, and they interact with some medications. Ashwagandha in particular should be used cautiously by women with thyroid conditions or hormone-sensitive cancers. Start with one adaptogen at a time, at the lowest effective dose, and give it six to eight weeks before evaluating results.

Cortisol Energy Stress
Radojka Barycki

Radojka Barycki

Licensed Zumba Instructor · Food Safety Executive · Founder, Fabulous At Any Age

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